Kenji Kangawa Selected Research

des-n-octanoyl ghrelin

1/2021	Importance of plasma ghrelin levels with special reference to nutritional metabolism and energy expenditure in pediatric patients with severe motor and intellectual disabilities.
1/2017	Therapeutic potential of ghrelin and des-acyl ghrelin against chemotherapy-induced cardiotoxicity.
2/2016	Des-acyl ghrelin prevents heatstroke-like symptoms in rats exposed to high temperature and high humidity.
5/2014	Circulating des-acyl ghrelin improves cardiovascular risk prediction in older hypertensive patients.
2/2013	Ghrelin prevents the development of experimental diabetic neuropathy in rodents.
11/2009	Ghrelin reverses experimental diabetic neuropathy in mice.
6/2009	Plasma des-acyl ghrelin, but not plasma HMW adiponectin, is a useful cardiometabolic marker for predicting atherosclerosis in elderly hypertensive patients.
11/2005	Relationship between growth and plasma concentrations of ghrelin and growth hormone in juvenile beagle dogs.
4/2005	Analysis of rat insulin II promoter-ghrelin transgenic mice and rat glucagon promoter-ghrelin transgenic mice.
11/2002	Plasma ghrelin and desacyl ghrelin concentrations in renal failure.

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Kenji Kangawa Research Topics

Disease

49	Body Weight (Weight, Body) 01/2021 - 07/2002
44	Heart Failure 01/2022 - 11/2002
30	Neoplasms (Cancer) 01/2022 - 11/2002
26	Myocardial Infarction 01/2019 - 05/2002
24	Obesity 01/2020 - 01/2002
23	Inflammation (Inflammations) 01/2020 - 06/2003
19	Pulmonary Hypertension 01/2019 - 02/2003
18	Cachexia 09/2015 - 02/2003
15	Fibrosis (Cirrhosis) 01/2020 - 01/2002
15	Ischemia 06/2019 - 02/2003
13	Weight Gain 01/2021 - 02/2002
12	Chronic Obstructive Pulmonary Disease (COPD) 11/2019 - 10/2004
12	Cardiovascular Diseases (Cardiovascular Disease) 01/2017 - 09/2004
12	Anorexia 09/2015 - 02/2003
11	Cardiomegaly (Heart Hypertrophy) 01/2020 - 11/2002
9	Hypoxia (Hypoxemia) 01/2019 - 02/2002
8	Cardiac Arrhythmias (Arrythmia) 06/2021 - 05/2009
8	Insulin Resistance 09/2018 - 12/2002
8	Weight Loss (Weight Reduction) 03/2016 - 02/2002
8	Starvation 01/2014 - 10/2002
8	Anorexia Nervosa 01/2012 - 01/2002
7	Heart Diseases (Heart Disease) 01/2019 - 06/2002
7	Hypertension (High Blood Pressure) 01/2017 - 06/2002
7	Infarction (Infarctions) 10/2013 - 12/2002
7	Pheochromocytoma 06/2013 - 04/2002
6	Neoplasm Metastasis (Metastasis) 01/2018 - 03/2015
6	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2017 - 12/2004
6	Esophageal Neoplasms (Esophageal Cancer) 08/2015 - 06/2006
6	Myocardial Ischemia (Ischemic Heart Diseases) 11/2013 - 02/2003
5	Congenital Heart Defects (Congenital Heart Defect) 01/2022 - 01/2018
5	Acute Lung Injury 01/2018 - 08/2007
5	Type 2 Diabetes Mellitus (MODY) 01/2017 - 01/2002
5	Myocarditis (Carditis) 09/2012 - 01/2007
5	Hyperplasia 04/2012 - 01/2002
5	Glomerulonephritis 11/2010 - 06/2003
4	Diabetes Mellitus 11/2019 - 08/2004
4	Reperfusion Injury 06/2019 - 02/2003
4	Melanoma (Melanoma, Malignant) 01/2018 - 02/2003
4	Respiratory Insufficiency (Respiratory Failure) 01/2018 - 12/2011
4	Acute Kidney Injury (Acute Renal Failure) 08/2017 - 01/2006
4	Lung Neoplasms (Lung Cancer) 01/2017 - 02/2003
4	Disease Progression 01/2017 - 01/2013
4	Ventricular Remodeling 12/2014 - 12/2002
4	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 10/2014 - 09/2004
4	Chronic Kidney Failure (Chronic Renal Failure) 01/2014 - 11/2002
4	Gastritis 04/2013 - 09/2004
4	Vascular Remodeling 09/2011 - 06/2002
4	AIDS-Related Complex (ARC) 11/2010 - 10/2005
4	Infections 10/2008 - 02/2003
4	Feeding and Eating Disorders (Eating Disorder) 01/2008 - 07/2002
4	Renal Insufficiency (Renal Failure) 01/2006 - 06/2002

Drug/Important Bio-Agent (IBA)

143	GhrelinIBA 01/2021 - 01/2002
59	AdrenomedullinIBA 06/2013 - 02/2002
28	Peptides (Polypeptides)IBA 01/2020 - 03/2002
25	Atrial Natriuretic Factor (ANF)IBA 01/2022 - 01/2002
17	Natriuretic PeptidesIBA 01/2022 - 11/2002
17	Messenger RNA (mRNA)IBA 01/2018 - 02/2003
16	C-Type Natriuretic Peptide (Peptide, C-Type Natriuretic)IBA 01/2019 - 06/2002
14	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 07/2003
12	Hormones (Hormone)IBA 01/2019 - 11/2002
12	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2019 - 04/2004
12	Insulin (Novolin)FDA Link 09/2018 - 02/2002
12	Growth Hormone (Somatotropin)IBA 11/2014 - 04/2003
10	des-n-octanoyl ghrelinIBA 01/2021 - 11/2002
10	MonocrotalineIBA 01/2019 - 08/2003
8	Biomarkers (Surrogate Marker)IBA 01/2019 - 01/2002
8	Cisplatin (Platino)FDA LinkGeneric 01/2018 - 10/2012
8	LipopolysaccharidesIBA 01/2018 - 12/2003
8	CollagenIBA 02/2016 - 01/2002
8	LeptinIBA 01/2016 - 12/2002
7	C-Reactive ProteinIBA 08/2015 - 08/2004
7	Vasodilator Agents (Vasodilators)IBA 10/2010 - 11/2002
6	Triglycerides (Triacylglycerol)IBA 11/2019 - 04/2005
6	CreatinineIBA 01/2017 - 11/2002
6	Bleomycin (Blenoxane)FDA LinkGeneric 01/2017 - 12/2004
6	Insulin-Like Growth Factor I (IGF-1)IBA 10/2014 - 11/2003
6	DNA (Deoxyribonucleic Acid)IBA 06/2005 - 07/2002
5	acyl-ghrelinIBA 01/2021 - 06/2006
5	Interleukin-6 (Interleukin 6)IBA 01/2019 - 11/2014
5	Blood Glucose (Blood Sugar)IBA 09/2018 - 01/2004
5	NeuropeptidesIBA 01/2018 - 07/2002
5	Ghrelin ReceptorsIBA 01/2017 - 07/2005
5	Proteins (Proteins, Gene)FDA Link 01/2017 - 05/2004
4	neuromedin UIBA 01/2020 - 10/2004
4	CytokinesIBA 01/2019 - 10/2008
4	atrial natriuretic factor receptor AIBA 01/2018 - 05/2008
4	Angiotensin IIIBA 01/2018 - 01/2002
4	gamma- aminobutyryl- 2- methyltryptophyl- 2- methyltryptophyl- 2- methyltryptophyl- lysinamideIBA 07/2017 - 12/2002
4	Pharmaceutical PreparationsIBA 09/2014 - 01/2004
4	AdiponectinIBA 06/2009 - 10/2006
4	Epoprostenol (Prostacyclin)FDA LinkGeneric 01/2008 - 12/2005
3	Anabolic AgentsIBA 01/2021 - 02/2003

Therapy/Procedure

18	Therapeutics 06/2021 - 01/2004
15	Transplantation 01/2019 - 08/2003
8	Ligation 06/2014 - 02/2003
7	Drug Therapy (Chemotherapy) 01/2018 - 02/2003
6	Gastrectomy 03/2016 - 01/2006
6	Esophagectomy 08/2015 - 06/2006
5	Intravenous Administration 10/2010 - 01/2004
4	Renal Dialysis (Hemodialysis) 01/2014 - 06/2003